The 13 C-urea breath test to detect Helicobacter pylori infection: a validated simple methodology with 50 mg 13 C-urea

The 13C-urea breath test to detect Helicobacter pylori infection: a validated simple methodology with 50 mg 13C-urea.

BACKGROUND Several modifications of the 13C-urea breath test have been published. For reasons of cost efficiency and practicability, the urea dose and measurement duration should be reduced while still maintaining excellent diagnostic accuracy. AIMS To establish a validated simple protocol for the urea breath test with 50 mg 13C-urea and to compare this protocol with the conventional urea bre...

Does low dose (13)C-urea breath test maintain a satisfactory accuracy in diagnosing Helicobacter pylori infection?

CONTEXT The standard doses of (13)C-urea in (13)C-urea breath test is 75 mg. OBJECTIVE To assess the diagnostic accuracy of (13)C-urea breath test containing 25 mg of (13)C-urea comparing with the standard doses of 75 mg in the diagnosis of Helicobacter pylori infection. METHODS Two hundred seventy adult patients (96 males, 174 females, median age 41 years) performed the standard (13)C-urea...

Appropriate Timing of the C-Urea Breath Test to Establish Eradication of Helicobacter pylori Infection

METHODS: Patients with active Helicobacter pylori infection at four medical centers received proton pump inhibitorbased triple or quadruple therapy for 10–14 days. Patients underwent the C-UBT 2 and 4–6 wk after the completion of therapy. A positive test was defined as CO2 excretion of .200 dpm, a negative test as ,50 dpm, and an equivocal test as .50 but ,200 dpm. Performance characteristics o...

The urea breath test for Helicobacter pylori.

The C urea breath test in the diagnosis of Helicobacter pylori infection

The urea breath test (UBT) is one of the most important non-invasive methods for detecting Helicobacter pylori infection. The test exploits the hydrolysis of orally administered urea by the enzyme urease, which H pylori produces in large quantities. Urea is hydrolysed to ammonia and carbon dioxide, which diVuses into the blood and is excreted by the lungs. Isotopically labelled CO2 can be detec...